Wave Life Sciences Ltd. is a clinical-stage genetic medicines company, which engages in the development of proprietary synthetic chemistry drug. The company employs 250 full-time employees The company went IPO on 2015-11-11. The company is engaged in developing oligonucleotides that target ribonucleic acid (RNA) and harness existing cellular machinery to reduce the expression of disease-promoting RNA or proteins, restore the production of functional proteins, or modulate protein expression. Its lead clinical development programs are designed to treat genetic diseases within the central nervous system (CNS), including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), Huntington’s disease (HD), and muscular dystrophies, including Duchenne muscular dystrophy (DMD). Its programs include WVE-004 (silencing), its C9orf72 molecule for the treatment of C9orf72-associated ALS and FTD, WVE-003 (silencing), its mHTT SNP3 molecule for the treatment of HD, and WVE-N531 (splicing), its exon 53 molecule for the treatment of DMD.